{"id":572,"date":"2025-11-24T12:49:44","date_gmt":"2025-11-24T12:49:44","guid":{"rendered":"https:\/\/info.ias.tuwien.ac.at\/bsc\/?page_id=572"},"modified":"2025-11-25T01:38:53","modified_gmt":"2025-11-25T01:38:53","slug":"mihovilovic-lab","status":"publish","type":"page","link":"https:\/\/info.ias.tuwien.ac.at\/bsc\/mihovilovic-lab\/","title":{"rendered":"Mihovilovic Lab"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"572\" class=\"elementor elementor-572\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-668ec27 e-con-full e-flex e-con e-parent\" data-id=\"668ec27\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-fa80375 e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"fa80375\" data-element_type=\"container\" 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Open items with Enter or Space, close with Escape and navigate using the Arrow keys.\">\n\t\t\t<div class=\"e-n-tabs-heading\" role=\"tablist\">\n\t\t\t\t\t<button id=\"e-n-tab-title-624793131\" class=\"e-n-tab-title\" aria-selected=\"true\" data-tab-index=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"e-n-tab-content-624793131\" style=\"--n-tabs-title-order: 1;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tResearch\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-624793132\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-624793132\" style=\"--n-tabs-title-order: 2;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tCV\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-624793133\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-624793133\" style=\"--n-tabs-title-order: 3;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tMembers\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-624793134\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-624793134\" style=\"--n-tabs-title-order: 4;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tProjects\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-624793135\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"5\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-624793135\" style=\"--n-tabs-title-order: 5;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tPublications\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-624793131\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-624793131\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-c802cdb e-con-full e-flex e-con e-child\" data-id=\"c802cdb\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-808546e e-con-full e-flex e-con e-child\" data-id=\"808546e\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ed267b4 elementor-widget elementor-widget-heading\" data-id=\"ed267b4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Research Topics:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6b064e0 elementor-widget elementor-widget-text-editor\" data-id=\"6b064e0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul><li>Research at the chemistry-biology interface.<\/li><li>Development and utilization of wild-type microorganisms and genetically engineered whole-cell systems as new tools in synthetic chemistry.<\/li><li>Design of multi-step biocatalytic and chemo-enzymatic reaction cascades.<\/li><li>Proliferation of the \u201cgreen chemistry\u201d concept with respect to sustainability, atom efficiency, and environmentally benign synthetic methods.<\/li><li>Development new bioactive compounds for modification of cell differentiation<\/li><li>Lead-optimization of natural-compound derived GABA<sub>A<\/sub>\u00a0ligands<\/li><li>Lead-optimization of natural-compound derived anti-inflammatory agents<\/li><li>Continuous flow chemical processes.<\/li><li>Utilization of chiral intermediates obtained via biocatalytic methods in natural compound total synthesis.<\/li><li>Development of platform technologies for renewables valorization and circular economy.<\/li><li>Exploitation of metal-assisted synthetic methods such as cross-coupling reactions (Negishi, Suzuki, Stille, Kumada), CH-activation, dircted\u00a0<i>ortho<\/i>-lithiation, cyclization reactions (Zn-mediated [4+3] cycloaddition, Pauson-Khand cyclization), and metathesis techniques (ring-opening metathesis, ring-closing metathesis).<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-624793132\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-624793132\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-8ee58a6 e-con-full e-flex e-con e-child\" data-id=\"8ee58a6\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-6284e44 e-con-full e-flex e-con e-child\" data-id=\"6284e44\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2632853 elementor-widget elementor-widget-text-editor\" data-id=\"2632853\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Marko was born in Steyr, Upper Austria, Austria in 1970. After the A-levels in Linz, he started to study Technical Chemistry \/ Organic Chemistry in 1988 at the Vienna University of Technology (VUT), Vienna, Austria. His diploma Thesis was entitled\u00a0<em>\u2018Synthesis of Thieno[2,3-d]thiadiazole Derivatives\u2019<\/em>\u00a0and was supervised by Prof. Peter Stanetty. He started his PhD thesis in 1994\u00a0<em>(\u2018Synthesis of Azasteroid Partial Structures as Potential Inhibitors of the Ergosterol Biosynthesis\u2019)<\/em>\u00a0again in the group of Prof. Peter Stanetty and finished this work in June 1996. From 1994-1998 he was research assistant at the Institute of Organic Chemistry (IOC). He was then on two postdoctoral stays as Erwin Schr\u00f6dinger Fellow of the FWF (Project no. J1471-CHEM\u00a0<em>(\u2018Designer Yeasts \u2013 New Bioreagents in enantioselective Synthesis\u2019)<\/em>\u00a0with Prof. Margaret M. Kayser University of New Brunswick, Saint John, N.B., Canada and Prof. Jon D. Stewart University of Florida, Gainesville, Florida, USA. From 1999-2003 he was again university assistant at the Institute of Applied Synthetic Chemistry (IAS, former IOC), VUT. In November 2003 he received his Habilitation (venia docendi) in the field of Bioorganic Chemistry and was promoted to \u2018University Dozent\u2019 (Assistant Professor) at the IAS, VUT. From March 2004 till January 2014 he was Associate University Professor at the IAS, VUT. In May 2008 he declined the appointment to Full Professor in Bioorganic Chemistry at Johannes Kepler University Linz, Austria. From 2009 up to now he coordinates the Graduate School Program AB-Tec (Applied Bioscience Technology) at Vienna University of Technology. Since January 2013 he is the Head of Institute at the Institute of Applied Synthetic Chemistry (Vienna University of Technology, Vienna, Austria). In February 2014 he was appointed as Full Professor and Chair for Bioorganic Synthetic Chemistry. He is Dean of the Faculty for Technical Chemistry, TU Wien since 2020.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-624793133\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-624793133\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-7e1c787 e-con-full e-flex e-con e-child\" data-id=\"7e1c787\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-527f18d e-con-full e-flex e-con e-child\" data-id=\"527f18d\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-624793134\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-624793134\" data-tab-index=\"4\" style=\"--n-tabs-title-order: 4;\" class=\" elementor-element elementor-element-ac8aaf7 e-flex e-con-boxed e-con e-child\" data-id=\"ac8aaf7\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-624793135\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-624793135\" data-tab-index=\"5\" style=\"--n-tabs-title-order: 5;\" class=\" elementor-element elementor-element-01c06c2 e-flex e-con-boxed e-con e-child\" data-id=\"01c06c2\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-9f6c419 e-con-full e-flex e-con e-child\" data-id=\"9f6c419\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7ab7ff4 e-con-full e-flex e-con e-child\" data-id=\"7ab7ff4\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b9f427b elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"b9f427b\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"288\" src=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-content\/uploads\/sites\/2\/2025\/11\/Profile-marko-mihovilovic-300x288-1.jpg\" class=\"attachment-full size-full wp-image-422\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Marko Mihovilovic<\/h3><p class=\"elementor-image-box-description\">Univ.Prof. Dipl.-Ing. Dr.techn.<br>\nDean Faculty of Chemistry<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1deed0b elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"1deed0b\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-content\/uploads\/sites\/2\/2025\/11\/Mihoviloviclab-logo-tile-150x150-1.png\" class=\"attachment-full size-full wp-image-418\" alt=\"\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Connect<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-56afb5e elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"56afb5e\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-phone-alt\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M497.39 361.8l-112-48a24 24 0 0 0-28 6.9l-49.6 60.6A370.66 370.66 0 0 1 130.6 204.11l60.6-49.6a23.94 23.94 0 0 0 6.9-28l-48-112A24.16 24.16 0 0 0 122.6.61l-104 24A24 24 0 0 0 0 48c0 256.5 207.9 464 464 464a24 24 0 0 0 23.4-18.6l24-104a24.29 24.29 0 0 0-14.01-27.6z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">+43 (1) 58801 - 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