{"id":799,"date":"2025-11-25T03:53:45","date_gmt":"2025-11-25T03:53:45","guid":{"rendered":"https:\/\/info.ias.tuwien.ac.at\/bsc\/?page_id=799"},"modified":"2025-11-25T14:30:06","modified_gmt":"2025-11-25T14:30:06","slug":"publications","status":"publish","type":"page","link":"https:\/\/info.ias.tuwien.ac.at\/bsc\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"799\" class=\"elementor elementor-799\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-668ec27 e-con-full e-flex e-con e-parent\" data-id=\"668ec27\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-fa80375 e-con-full elementor-hidden-tablet elementor-hidden-mobile e-flex e-con e-child\" data-id=\"fa80375\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c80b9c2 elementor-nav-menu--dropdown-tablet elementor-nav-menu__text-align-aside elementor-nav-menu--toggle elementor-nav-menu--burger elementor-widget elementor-widget-nav-menu\" data-id=\"c80b9c2\" data-element_type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;},&quot;toggle&quot;:&quot;burger&quot;}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"Menu\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-c80b9c2\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-773\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/\" class=\"elementor-item menu-link\">Home<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-674\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/rudroff-lab\/\" class=\"elementor-item menu-link\">Rudroff Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-582\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/schnuerch-lab\/\" class=\"elementor-item menu-link\">Sch\u00adn\u00fcrch Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-579\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/mihovilovic-lab\/\" class=\"elementor-item menu-link\">Mihovilovic Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-583\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/stanetty-lab\/\" class=\"elementor-item menu-link\">Stanetty Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-860\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/members\/\" class=\"elementor-item menu-link\">Members<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-811\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/publications\/\" class=\"elementor-item menu-link\">Publications<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t<div class=\"elementor-menu-toggle\" role=\"button\" tabindex=\"0\" aria-label=\"Menu Toggle\" aria-expanded=\"false\">\n\t\t\t<svg aria-hidden=\"true\" role=\"presentation\" class=\"elementor-menu-toggle__icon--open e-font-icon-svg e-eicon-menu-bar\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M104 333H896C929 333 958 304 958 271S929 208 896 208H104C71 208 42 237 42 271S71 333 104 333ZM104 583H896C929 583 958 554 958 521S929 458 896 458H104C71 458 42 487 42 521S71 583 104 583ZM104 833H896C929 833 958 804 958 771S929 708 896 708H104C71 708 42 737 42 771S71 833 104 833Z\"><\/path><\/svg><svg aria-hidden=\"true\" role=\"presentation\" class=\"elementor-menu-toggle__icon--close e-font-icon-svg e-eicon-close\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M742 167L500 408 258 167C246 154 233 150 217 150 196 150 179 158 167 167 154 179 150 196 150 212 150 229 154 242 171 254L408 500 167 742C138 771 138 800 167 829 196 858 225 858 254 829L496 587 738 829C750 842 767 846 783 846 800 846 817 842 829 829 842 817 846 804 846 783 846 767 842 750 829 737L588 500 833 258C863 229 863 200 833 171 804 137 775 137 742 167Z\"><\/path><\/svg>\t\t<\/div>\n\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-c80b9c2\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-773\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Home<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-674\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/rudroff-lab\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Rudroff Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-582\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/schnuerch-lab\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Sch\u00adn\u00fcrch Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-579\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/mihovilovic-lab\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Mihovilovic Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-583\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/stanetty-lab\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Stanetty Lab<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-860\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/members\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Members<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-811\"><a href=\"https:\/\/info.ias.tuwien.ac.at\/bsc\/publications\/\" class=\"elementor-item menu-link\" tabindex=\"-1\">Publications<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ba7ce39 elementor-shape-rounded elementor-grid-0 elementor-widget elementor-widget-social-icons\" data-id=\"ba7ce39\" data-element_type=\"widget\" data-widget_type=\"social-icons.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-social-icons-wrapper elementor-grid\" role=\"list\">\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-facebook elementor-repeater-item-51c9b2a\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Facebook<\/span>\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fab-facebook\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256C504 119 393 8 256 8S8 119 8 256c0 123.78 90.69 226.38 209.25 245V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.31 482.38 504 379.78 504 256z\"><\/path><\/svg>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-twitter elementor-repeater-item-c847ba4\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Twitter<\/span>\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fab-twitter\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M459.37 151.716c.325 4.548.325 9.097.325 13.645 0 138.72-105.583 298.558-298.558 298.558-59.452 0-114.68-17.219-161.137-47.106 8.447.974 16.568 1.299 25.34 1.299 49.055 0 94.213-16.568 130.274-44.832-46.132-.975-84.792-31.188-98.112-72.772 6.498.974 12.995 1.624 19.818 1.624 9.421 0 18.843-1.3 27.614-3.573-48.081-9.747-84.143-51.98-84.143-102.985v-1.299c13.969 7.797 30.214 12.67 47.431 13.319-28.264-18.843-46.781-51.005-46.781-87.391 0-19.492 5.197-37.36 14.294-52.954 51.655 63.675 129.3 105.258 216.365 109.807-1.624-7.797-2.599-15.918-2.599-24.04 0-57.828 46.782-104.934 104.934-104.934 30.213 0 57.502 12.67 76.67 33.137 23.715-4.548 46.456-13.32 66.599-25.34-7.798 24.366-24.366 44.833-46.132 57.827 21.117-2.273 41.584-8.122 60.426-16.243-14.292 20.791-32.161 39.308-52.628 54.253z\"><\/path><\/svg>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<span class=\"elementor-grid-item\" role=\"listitem\">\n\t\t\t\t\t<a class=\"elementor-icon elementor-social-icon elementor-social-icon-youtube elementor-repeater-item-93111e1\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-screen-only\">Youtube<\/span>\n\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fab-youtube\" viewBox=\"0 0 576 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M549.655 124.083c-6.281-23.65-24.787-42.276-48.284-48.597C458.781 64 288 64 288 64S117.22 64 74.629 75.486c-23.497 6.322-42.003 24.947-48.284 48.597-11.412 42.867-11.412 132.305-11.412 132.305s0 89.438 11.412 132.305c6.281 23.65 24.787 41.5 48.284 47.821C117.22 448 288 448 288 448s170.78 0 213.371-11.486c23.497-6.321 42.003-24.171 48.284-47.821 11.412-42.867 11.412-132.305 11.412-132.305s0-89.438-11.412-132.305zm-317.51 213.508V175.185l142.739 81.205-142.739 81.201z\"><\/path><\/svg>\t\t\t\t\t<\/a>\n\t\t\t\t<\/span>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3132580 e-con-full e-flex e-con e-child\" data-id=\"3132580\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-5b2fb39 e-con-full e-flex e-con e-child\" data-id=\"5b2fb39\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2e4d83e elementor-widget elementor-widget-heading\" data-id=\"2e4d83e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-56cc99a e-con-full e-flex e-con e-child\" data-id=\"56cc99a\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-5750cfdf e-con-full e-flex e-con e-child\" data-id=\"5750cfdf\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-3f99dcaf e-con-full e-flex e-con e-child\" data-id=\"3f99dcaf\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2997af7 jet-smart-filter-content-position-column jet-smart-filter-group-position-column elementor-widget elementor-widget-jet-smart-filters-select\" data-id=\"2997af7\" data-element_type=\"widget\" data-widget_type=\"jet-smart-filters-select.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"jet-smart-filters-select jet-filter \" data-indexer-rule=\"show\" data-show-counter=\"\" data-change-counter=\"always\"><div class=\"jet-select\" data-query-type=\"tax_query\" data-query-var=\"publication_year\" data-smart-filter=\"select\" data-filter-id=\"167\" data-apply-type=\"ajax\" data-content-provider=\"jet-engine\" data-additional-providers=\"\" data-query-id=\"default\" data-active-label=\"Year:\" data-layout-options=\"{&quot;show_label&quot;:&quot;&quot;,&quot;display_options&quot;:{&quot;show_items_label&quot;:false,&quot;show_decorator&quot;:false,&quot;filter_image_size&quot;:&quot;full&quot;,&quot;show_counter&quot;:false}}\" data-query-var-suffix=\"\" data-apply-on=\"value\">\n\t\t\t\t<select\n\t\t\tclass=\"jet-select__control\"\n\t\t\tname=\"publication_year\"\n\t\t\t\t\t\taria-label=\"Publication Year\"\n\t\t>\n\t\t\n\t\t\t\t\t<option\n\t\t\t\tvalue=\"\"\n\t\t\t\tdata-label=\"Year\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Year<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"16\"\n\t\t\t\tdata-label=\"2026\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>2026<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"19\"\n\t\t\t\tdata-label=\"2025\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>2025<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"27\"\n\t\t\t\tdata-label=\"2024\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>2024<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"20\"\n\t\t\t\tdata-label=\"2023\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>2023<\/option>\n\t\t\t<\/select>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0587ac jet-smart-filter-content-position-column jet-smart-filter-group-position-column elementor-widget elementor-widget-jet-smart-filters-select\" data-id=\"c0587ac\" data-element_type=\"widget\" data-widget_type=\"jet-smart-filters-select.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"jet-smart-filters-select jet-filter \" data-indexer-rule=\"show\" data-show-counter=\"\" data-change-counter=\"always\"><div class=\"jet-select\" data-query-type=\"tax_query\" data-query-var=\"working_group\" data-smart-filter=\"select\" data-filter-id=\"166\" data-apply-type=\"ajax\" data-content-provider=\"jet-engine\" data-additional-providers=\"\" data-query-id=\"default\" data-active-label=\"Working Group:\" data-layout-options=\"{&quot;show_label&quot;:&quot;&quot;,&quot;display_options&quot;:{&quot;show_items_label&quot;:false,&quot;show_decorator&quot;:false,&quot;filter_image_size&quot;:&quot;full&quot;,&quot;show_counter&quot;:false}}\" data-query-var-suffix=\"\" data-apply-on=\"value\">\n\t\t\t\t<select\n\t\t\tclass=\"jet-select__control\"\n\t\t\tname=\"working_group\"\n\t\t\t\t\t\taria-label=\"Working Group\"\n\t\t>\n\t\t\n\t\t\t\t\t<option\n\t\t\t\tvalue=\"\"\n\t\t\t\tdata-label=\"Working Group\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Working Group<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"29\"\n\t\t\t\tdata-label=\"Rudroff Lab\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Rudroff Lab<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"14\"\n\t\t\t\tdata-label=\"Schn\u00fcrch Lab\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Schn\u00fcrch Lab<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"26\"\n\t\t\t\tdata-label=\"Stanetty Lab\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Stanetty Lab<\/option>\n\t\t\t<\/select>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-af27478 jet-smart-filter-content-position-column jet-smart-filter-group-position-column elementor-widget elementor-widget-jet-smart-filters-select\" data-id=\"af27478\" data-element_type=\"widget\" data-widget_type=\"jet-smart-filters-select.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"jet-smart-filters-select jet-filter \" data-indexer-rule=\"show\" data-show-counter=\"\" data-change-counter=\"always\"><div class=\"jet-select\" data-query-type=\"tax_query\" data-query-var=\"member\" data-smart-filter=\"select\" data-filter-id=\"165\" data-apply-type=\"ajax\" data-content-provider=\"jet-engine\" data-additional-providers=\"\" data-query-id=\"default\" data-active-label=\"Group Member:\" data-layout-options=\"{&quot;show_label&quot;:&quot;&quot;,&quot;display_options&quot;:{&quot;show_items_label&quot;:false,&quot;show_decorator&quot;:false,&quot;filter_image_size&quot;:&quot;full&quot;,&quot;show_counter&quot;:false}}\" data-query-var-suffix=\"\" data-apply-on=\"value\">\n\t\t\t\t<select\n\t\t\tclass=\"jet-select__control\"\n\t\t\tname=\"member\"\n\t\t\t\t\t\taria-label=\"Group Member\"\n\t\t>\n\t\t\n\t\t\t\t\t<option\n\t\t\t\tvalue=\"\"\n\t\t\t\tdata-label=\"Member\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Member<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"23\"\n\t\t\t\tdata-label=\"Christian Stanetty\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Christian Stanetty<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"30\"\n\t\t\t\tdata-label=\"Florian Rudroff\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Florian Rudroff<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"31\"\n\t\t\t\tdata-label=\"Lydia Suchy\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Lydia Suchy<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"25\"\n\t\t\t\tdata-label=\"Markus Draskovits\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Markus Draskovits<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"15\"\n\t\t\t\tdata-label=\"Michael Schn\u00fcrch\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Michael Schn\u00fcrch<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"24\"\n\t\t\t\tdata-label=\"Nicolas Kratena\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Nicolas Kratena<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"18\"\n\t\t\t\tdata-label=\"Nina Biedermann\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Nina Biedermann<\/option>\n\t\t\t<\/select>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-02cfe2a jet-smart-filter-content-position-column jet-smart-filter-group-position-column elementor-widget elementor-widget-jet-smart-filters-select\" data-id=\"02cfe2a\" data-element_type=\"widget\" data-widget_type=\"jet-smart-filters-select.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"jet-smart-filters-select jet-filter \" data-indexer-rule=\"show\" data-show-counter=\"\" data-change-counter=\"always\"><div class=\"jet-select\" data-query-type=\"tax_query\" data-query-var=\"journal\" data-smart-filter=\"select\" data-filter-id=\"172\" data-apply-type=\"ajax\" data-content-provider=\"jet-engine\" data-additional-providers=\"\" data-query-id=\"default\" data-active-label=\"Journal:\" data-layout-options=\"{&quot;show_label&quot;:&quot;&quot;,&quot;display_options&quot;:{&quot;show_items_label&quot;:false,&quot;show_decorator&quot;:false,&quot;filter_image_size&quot;:&quot;full&quot;,&quot;show_counter&quot;:false}}\" data-query-var-suffix=\"\" data-apply-on=\"value\">\n\t\t\t\t<select\n\t\t\tclass=\"jet-select__control\"\n\t\t\tname=\"journal\"\n\t\t\t\t\t\taria-label=\"Journal\"\n\t\t>\n\t\t\n\t\t\t\t\t<option\n\t\t\t\tvalue=\"\"\n\t\t\t\tdata-label=\"Journal\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Journal<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"21\"\n\t\t\t\tdata-label=\"Analytica Chimica Acta\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>Analytica Chimica Acta<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"28\"\n\t\t\t\tdata-label=\"ChemCatChem\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>ChemCatChem<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"13\"\n\t\t\t\tdata-label=\"European Journal of Medicinal Chemistry\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>European Journal of Medicinal Chemistry<\/option>\n\t\t\t\t\t\t<option\n\t\t\t\tvalue=\"17\"\n\t\t\t\tdata-label=\"RSC Mechanochemistry\"\n\t\t\t\tdata-counter-prefix=\"\"\n\t\t\t\tdata-counter-suffix=\"\"\n\t\t\t\t\t\t\t\t\t\t\t>RSC Mechanochemistry<\/option>\n\t\t\t<\/select>\n\t<\/div>\n<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-49dbd869 elementor-grid-1 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid\" data-id=\"49dbd869\" data-element_type=\"widget\" data-settings=\"{&quot;template_id&quot;:&quot;786&quot;,&quot;columns&quot;:1,&quot;_skin&quot;:&quot;post&quot;,&quot;columns_tablet&quot;:&quot;2&quot;,&quot;columns_mobile&quot;:&quot;1&quot;,&quot;edit_handle_selector&quot;:&quot;[data-elementor-type=\\&quot;loop-item\\&quot;]&quot;,&quot;row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"loop-grid.post\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-loop-container elementor-grid\" role=\"list\">\n\t\t<style id=\"loop-786\">.elementor-786 .elementor-element.elementor-element-32b779a{--display:flex;--flex-direction:row;--container-widget-width:calc( ( 1 - var( --container-widget-flex-grow ) ) * 100% );--container-widget-height:100%;--container-widget-flex-grow:1;--container-widget-align-self:stretch;--flex-wrap-mobile:wrap;--justify-content:flex-start;--align-items:flex-start;--gap:0px 0px;--row-gap:0px;--column-gap:0px;}.elementor-786 .elementor-element.elementor-element-32b779a.e-con{--align-self:flex-start;--order:-99999 \/* order start hack *\/;}.elementor-786 .elementor-element.elementor-element-d533516{--display:flex;--flex-direction:column;--container-widget-width:calc( ( 1 - var( --container-widget-flex-grow ) ) * 100% );--container-widget-height:initial;--container-widget-flex-grow:0;--container-widget-align-self:initial;--flex-wrap-mobile:wrap;--justify-content:flex-start;--align-items:flex-start;--gap:0px 0px;--row-gap:0px;--column-gap:0px;}.elementor-786 .elementor-element.elementor-element-d533516.e-con{--align-self:flex-start;--order:-99999 \/* order start hack *\/;}.elementor-widget-theme-post-title .elementor-heading-title{font-family:var( --e-global-typography-primary-font-family ), Sans-serif;font-weight:var( --e-global-typography-primary-font-weight );color:var( --e-global-color-primary );}.elementor-786 .elementor-element.elementor-element-4abc60a .elementor-heading-title{font-family:\"Roboto\", Sans-serif;font-size:1.4em;font-weight:600;color:#006699;}.elementor-widget-text-editor{font-family:var( --e-global-typography-text-font-family ), Sans-serif;font-weight:var( --e-global-typography-text-font-weight );color:var( --e-global-color-text );}.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:var( --e-global-color-primary );}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap, .elementor-widget-text-editor.elementor-drop-cap-view-default .elementor-drop-cap{color:var( --e-global-color-primary );border-color:var( --e-global-color-primary );}.elementor-786 .elementor-element.elementor-element-afeb126{font-family:\"Roboto\", Sans-serif;font-size:0.9em;font-weight:400;color:#535353;}.elementor-786 .elementor-element.elementor-element-5cf6517{padding:0px 0px 0px 0px;font-family:\"Roboto\", Sans-serif;font-size:0.9em;font-weight:400;color:#535353;}.elementor-786 .elementor-element.elementor-element-4389ef6{margin:0px 0px calc(var(--kit-widget-spacing, 0px) + 10px) 0px;font-family:\"Roboto\", Sans-serif;font-size:0.9em;font-weight:500;color:#006699;}.elementor-786 .elementor-element.elementor-element-b72aba0{--display:flex;}.elementor-786 .elementor-element.elementor-element-5f4eca3{--display:flex;--flex-direction:row;--container-widget-width:initial;--container-widget-height:100%;--container-widget-flex-grow:1;--container-widget-align-self:stretch;--flex-wrap-mobile:wrap;--gap:0px 0px;--row-gap:0px;--column-gap:0px;}.elementor-786 .elementor-element.elementor-element-f02fe7d{--n-accordion-title-font-size:1rem;--n-accordion-title-justify-content:initial;--n-accordion-title-flex-grow:initial;--n-accordion-title-icon-order:-1;--n-accordion-item-title-space-between:0px;--n-accordion-item-title-distance-from-content:0px;--n-accordion-icon-size:15px;}<\/style>\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"786\" class=\"elementor elementor-786 e-loop-item e-loop-item-915 post-915 publication type-publication status-publish hentry publication_year-27 journal-chemcatchem working_group-rudroff-lab member-florian-rudroff member-lydia-suchy\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-32b779a e-con-full e-flex e-con e-parent\" data-id=\"32b779a\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d533516 e-con-full e-flex e-con e-parent\" data-id=\"d533516\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4abc60a elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"4abc60a\" data-element_type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">In situ Generation of Aldehydes for Subsequent Biocatalytic Cascade Reactions in Whole Cells<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afeb126 elementor-widget elementor-widget-text-editor\" data-id=\"afeb126\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tLydia Suchy and Florian Rudroff*\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cf6517 elementor-widget elementor-widget-text-editor\" data-id=\"5cf6517\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tChemCatChem\u00a0<strong>2024<\/strong>, 16, e202301138\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4389ef6 elementor-widget elementor-widget-text-editor\" data-id=\"4389ef6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\thttps:\/\/doi.org\/10.1002\/cctc.202301138\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f02fe7d elementor-widget elementor-widget-n-accordion\" data-id=\"f02fe7d\" data-element_type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2510\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2510\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Abstract <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-b72aba0 e-con-full e-flex e-con e-child\" data-id=\"b72aba0\" data-element_type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-5f4eca3 e-flex e-con-boxed e-con e-child\" data-id=\"5f4eca3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4656855 elementor-widget elementor-widget-text-editor\" data-id=\"4656855\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Aldehydes are highly reactive compounds. Byproduct formation to the corresponding alcohol or carboxylic acid in E. coli can be avoided by enzymes with reversing activity (alcohol dehydrogenase ADH and carboxylic acid reductase CAR). This concept was expanded by three new enzymes: pyruvate decarboxylase PDC, \u03c9-transaminase \u03c9-TA and imine reductase IRED. That enabled the synthesis of \u03b1-hydroxy ketones, primary and secondary amines in E. coli.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"786\" class=\"elementor elementor-786 e-loop-item e-loop-item-882 post-882 publication type-publication status-publish hentry publication_year-20 journal-analytica-chimica-acta working_group-stanetty-lab member-christian-stanetty member-markus-draskovits member-nicolas-kratena\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-32b779a e-con-full e-flex e-con e-parent\" data-id=\"32b779a\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d533516 e-con-full e-flex e-con e-parent\" data-id=\"d533516\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4abc60a elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"4abc60a\" data-element_type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Surveying the mugineic acid family: Ion mobility \u2013 quadrupole time-of-flight mass spectrometry (IM-QTOFMS) characterization and tandem mass spectrometry (LC-ESI-MS\/MS) quantification of all eight naturally occurring phytosiderophores<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afeb126 elementor-widget elementor-widget-text-editor\" data-id=\"afeb126\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tAndreea Spiridon, Eva Oburger, Younes Valadbeigi, Tobias Kloimb\u00f6ck, Christian Stanetty, Nicolas Kratena, Markus Draskovits, Tim Causon, Stephan Hann*\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cf6517 elementor-widget elementor-widget-text-editor\" data-id=\"5cf6517\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tAnalytica Chimica Acta <strong>2023,<\/strong> 1278, 341718\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f02fe7d elementor-widget elementor-widget-n-accordion\" data-id=\"f02fe7d\" data-element_type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2510\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2510\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Abstract <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-b72aba0 e-con-full e-flex e-con e-child\" data-id=\"b72aba0\" data-element_type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-5f4eca3 e-flex e-con-boxed e-con e-child\" data-id=\"5f4eca3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4656855 elementor-widget elementor-widget-text-editor\" data-id=\"4656855\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><a class=\"topic-link\" title=\"Learn more about Phytosiderophores from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/phytosiderophore\">Phytosiderophores<\/a>\u00a0(PS) are root exudates released by grass species (<em>Poaceae<\/em>) that play a pivotal role in iron (Fe) plant nutrition. A direct determination of PS in biological samples is of paramount importance in understanding\u00a0<a class=\"topic-link\" title=\"Learn more about micronutrient from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/micronutrient\">micronutrient<\/a>\u00a0acquisition mediated by PS. To date, eight plant-born PS have been identified; however, no analytical procedure is currently available to quantify all eight PS simultaneously with high analytical confidence. With access to the full set of PS standards for the first time, we report comprehensive methods to both fully characterize (IM-QTOFMS) and quantify (LC-ESI-MS\/MS) all eight naturally occurring PS belonging to the\u00a0<a class=\"topic-link\" title=\"Learn more about mugineic acid from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/mugineic-acid\">mugineic acid<\/a>\u00a0family. The\u00a0<a class=\"topic-link\" title=\"Learn more about quantitative method from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/quantitative-technique\">quantitative method<\/a>\u00a0was fully validated, yielding linear results for all eight analytes, and no unwanted interferences with soil and plant matrices were observed. LOD and LOQ values determined for each PS were below 11 and 35\u00a0nmol\u00a0L<sup>\u22121<\/sup>, respectively. The method\u2019s precision under reproducibility conditions (intra- and inter-day) of measurement was less than 2.5% RSD for all analytes. Additionally, all PS were annotated with high-resolution mass spectrometric fragment spectra and further characterized via drift tube ion mobility-mass spectrometry. The collision cross-sections obtained for primary ion species yielded a valuable database for future research focused on in-depth PS studies. The new quantitative method was applied to analyse root exudates from Fe-controlled and deficient barley, oat, rye, and sorghum plants. All eight PS, including mugineic acid (MA), 3\u2033-hydroxymugineic acid (HMA), 3\u2033-<em>epi<\/em>-hydroxymugineic acid (<em>epi<\/em>-HMA), hydroxyavenic acid (HAVA), deoxymugineic acid (DMA), 3\u2033-hydroxydeoxymugineic acid (HDMA), 3\u2033-<em>epi<\/em>-hydroxydeoxymugineic acid (<em>epi<\/em>-HDMA) and avenic acid (AVA) were for the first time successfully identified and quantified in root exudates of various\u00a0<a class=\"topic-link\" title=\"Learn more about graminaceous plants from ScienceDirect's AI-generated Topic Pages\" href=\"https:\/\/www.sciencedirect.com\/topics\/earth-and-planetary-sciences\/graminaceous-plant\">graminaceous plants<\/a>\u00a0using a single analytical procedure. These newly developed methods can be applied to studies aimed at improving crop yield and micronutrient grain content for food consumption via plant-based biofortification.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"786\" class=\"elementor elementor-786 e-loop-item e-loop-item-100 post-100 publication type-publication status-publish hentry publication_year-16 journal-european-journal-of-medicinal-chemistry working_group-schnurch-lab member-michael-schnurch\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-32b779a e-con-full e-flex e-con e-parent\" data-id=\"32b779a\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d533516 e-con-full e-flex e-con e-parent\" data-id=\"d533516\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4abc60a elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"4abc60a\" data-element_type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Identification of a novel PDE4 inhibitor inspired by leoligin-derived lignans<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afeb126 elementor-widget elementor-widget-text-editor\" data-id=\"afeb126\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tChristine Coffey, Alexander F. Perhal*, Wito Richter, Ya Chen, Thomas Linder, Stefan Schwaiger, Marko D. Mihovilovic, Johannes Kirchmair, Michael Schn\u00fcrch, Verena M. Dirsch\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cf6517 elementor-widget elementor-widget-text-editor\" data-id=\"5cf6517\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tEuropean Journal of Medicinal Chemistry <strong>2026<\/strong>, 302, 118285\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4389ef6 elementor-widget elementor-widget-text-editor\" data-id=\"4389ef6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\thttps:\/\/doi.org\/10.1016\/j.ejmech.2025.118285\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f02fe7d elementor-widget elementor-widget-n-accordion\" data-id=\"f02fe7d\" data-element_type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2510\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2510\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Abstract <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-b72aba0 e-con-full e-flex e-con e-child\" data-id=\"b72aba0\" data-element_type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-5f4eca3 e-flex e-con-boxed e-con e-child\" data-id=\"5f4eca3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4656855 elementor-widget elementor-widget-text-editor\" data-id=\"4656855\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The phosphodiesterase 4 (PDE4) family comprises isoenzymes that selectively hydrolyse the second messenger cyclic adenosine monophosphate (cAMP). PDE4s are widely expressed and play key roles in various physiologic paradigms, including immune responses, memory, cognition, and metabolism. Marketed PDE4 inhibitors, such as roflumilast and apremilast, treat chronic obstructive pulmonary disease and psoriasis. Identification and characterisation of PDE4 inhibitors offer a promising strategy for targeting diverse pathological processes. In this study, leoligin, a natural lignan found in the roots of Edelweiss (<em>Leontopodium nivale<\/em>\u00a0subsp.\u00a0<em>alpinum<\/em>\u00a0(Cass.) Greuter (Asteraceae)) and 165 analogues were screened for their PDE inhibitory activity using a cAMP accumulation assay employing an exchange protein activated by cAMP-based biosensor. Six compounds, including leoligin itself, were identified to cause a significant accumulation of cAMP, and structure-activity relationships were deduced. One analogue, designated\u00a0<em>LT-104A<\/em>, showed a concentration-dependent activity with the highest determined potency (EC<sub>50<\/sub>\u00a0=\u00a01.9\u00a0\u03bcM) in the cAMP accumulation assay.\u00a0<em>LT-104A<\/em>\u00a0was further characterised using a CRE-Luciferase assay, showing comparable activity to known PDE4 inhibitors in inducing the anti-inflammatory cAMP-PKA-CREB pathway. The inhibitory activity of\u00a0<em>LT-104A<\/em>\u00a0was also confirmed against recombinant PDE4D3 in a cell-free cAMP hydrolysis assay (IC<sub>50<\/sub>\u00a0=\u00a09.3\u00a0\u03bcM). The potential binding mode of\u00a0<em>LT-104A<\/em>\u00a0with the catalytic domain of PDE4D was predicted using induced-fit docking. Lastly, a functional study was conducted in LPS-activated macrophages, where\u00a0<em>LT-104A<\/em>\u00a0reduced nitric oxide release and decreased mRNA expression of\u00a0<em>Il1b<\/em>\u00a0and\u00a0<em>Nos2<\/em>. In conclusion, extensive in vitro screening of leoligin analogues led to the identification and characterisation of a novel PDE4 inhibitor,\u00a0<em>LT-104A<\/em>, with potential in vitro anti-inflammatory properties.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-elementor-type=\"loop-item\" data-elementor-id=\"786\" class=\"elementor elementor-786 e-loop-item e-loop-item-62 post-62 publication type-publication status-publish hentry publication_year-19 journal-rsc-mechanochemistry working_group-schnurch-lab member-michael-schnurch member-nina-biedermann\" data-elementor-post-type=\"elementor_library\" data-custom-edit-handle=\"1\">\n\t\t\t<div class=\"elementor-element elementor-element-32b779a e-con-full e-flex e-con e-parent\" data-id=\"32b779a\" data-element_type=\"container\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d533516 e-con-full e-flex e-con e-parent\" data-id=\"d533516\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4abc60a elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"4abc60a\" data-element_type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Mechanically induced sequential one-pot Wittig olefination\u2013Diels\u2013Alder reaction: a solvent-free approach to complex bicyclic scaffolds<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afeb126 elementor-widget elementor-widget-text-editor\" data-id=\"afeb126\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tNina Biedermann and  Michael Schn\u00fcrch*\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cf6517 elementor-widget elementor-widget-text-editor\" data-id=\"5cf6517\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<i>RSC Mechanochem.<\/i>, <strong>2025<\/strong>, 2, 879-888\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4389ef6 elementor-widget elementor-widget-text-editor\" data-id=\"4389ef6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\thttps:\/\/doi.org\/10.1039\/D5MR00087D\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f02fe7d elementor-widget elementor-widget-n-accordion\" data-id=\"f02fe7d\" data-element_type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2510\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2510\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Abstract <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-b72aba0 e-con-full e-flex e-con e-child\" data-id=\"b72aba0\" data-element_type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2510\" class=\"elementor-element elementor-element-5f4eca3 e-flex e-con-boxed e-con e-child\" data-id=\"5f4eca3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4656855 elementor-widget elementor-widget-text-editor\" data-id=\"4656855\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Herein we present a mechanically induced, solvent-free protocol that sequentially combines the Wittig olefination and Diels\u2013Alder cycloaddition in one-pot and enables the synthesis of structurally complex bicyclic compounds. This method proceeds entirely under ball milling conditions without the requirement of any solvent while eliminating the need for intermediate purification. Careful optimization of the milling parameters and reagent addition enables efficient conversion of various \u03b1,\u03b2-unsaturated aldehydes and ketones with electron-deficient dienophiles to the corresponding cycloadducts\u00a0<em>via<\/em>\u00a0diene intermediates, demonstrating high stereoselectivity and yielding exclusively\u00a0<em>endo<\/em>\u00a0Diels\u2013Alder adducts. Furthermore, the extension of the sequence by a solvent-free one-pot oxidation is exemplified, achieving a three-step synthesis in a single milling vessel without intermediate workup and purification, which exhibits excellent green metrics in comparison with solution-based methods. This operationally simple and sustainable approach demonstrates the potential of mechanochemistry to streamline multistep organic synthesis, while reducing solvent use and energy demand.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Facebook Twitter Youtube Year2026202520242023 Working GroupRudroff LabSchn\u00fcrch LabStanetty Lab MemberChristian StanettyFlorian RudroffLydia SuchyMarkus DraskovitsMichael Schn\u00fcrchNicolas KratenaNina Biedermann JournalAnalytica Chimica ActaChemCatChemEuropean [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"disabled","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-799","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/pages\/799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/comments?post=799"}],"version-history":[{"count":45,"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/pages\/799\/revisions"}],"predecessor-version":[{"id":919,"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/pages\/799\/revisions\/919"}],"wp:attachment":[{"href":"https:\/\/info.ias.tuwien.ac.at\/bsc\/wp-json\/wp\/v2\/media?parent=799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}