BioZone Project by Florian Rudroff approved by FWF

We are happy to announce that Florian Rudroff was granted FWF Project with title, Biologisch inspirierte Alkenspaltung – BioZone

Post-rudrofflab-Biozone-scheme







The key scientific challenges are the following:

  • Find a biochemical substitute to the well-established chemical ozonolysis.
  • Development of chemical probes to screen Nature’s huge sequence space efficiently and accurately.
  • Novel biocatalyst: broad substrate scope, use a mild, cheap and sustainable oxidant (O2, air).
  • Gain a deeper understanding of structure-function relationships for alkene cleaving NISEs.
  • Easily expressible in a classical production host like E. coli & show a high process stability.
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